Details for gene set NCI_IL12-MEDIATED SIGNALING EVENTS[GSEA]

Table: GSEA Results Summary

Dataset	Set_01_SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus.phenotype_SCID_versus_ATM_plus.cls #SCID_versus_ATM_plus_repos
Phenotype	phenotype_SCID_versus_ATM_plus.cls#SCID_versus_ATM_plus_repos
Upregulated in class	ATM_plus
GeneSet	NCI_IL12-MEDIATED SIGNALING EVENTS
Enrichment Score (ES)	-0.57856166
Normalized Enrichment Score (NES)	-1.7720698
Nominal p-value	0.0
FDR q-value	0.081622936
FWER p-Value	0.321

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	GZMA	1417898_a_at	140	3.145	0.0375	No
2	TBX21	1449361_at	242	2.572	0.0689	No
3	UBE2D3	1423112_at 1423113_a_at 1423114_at 1450858_a_at 1450859_s_at 1455479_a_at 1455480_s_at	492	1.840	0.0832	No
4	TRAF6	1421376_at 1421377_at 1435350_at 1443288_at 1446940_at 1446977_at	1376	0.896	0.0553	No
5	IL12RB2	1421623_at	1491	0.844	0.0619	No
6	MALT1	1445068_at 1456126_at 1456429_at	1510	0.836	0.0727	No
7	TNFAIP3	1433699_at 1450829_at	1881	0.674	0.0652	No
8	MAPK14	1416703_at 1416704_at 1426104_at 1442364_at 1451927_a_at 1459617_at	2079	0.612	0.0647	No
9	MAPK8	1420931_at 1420932_at 1437045_at 1440856_at 1457936_at	2363	0.538	0.0593	No
10	IL12RB1	1418166_at	2751	0.460	0.0480	No
11	PIK3CA	1423144_at 1429434_at 1429435_x_at 1440054_at 1453134_at 1460326_at	2775	0.456	0.0533	No
12	ATM	1421205_at 1428830_at	2801	0.453	0.0585	No
13	CCL3	1419561_at	3075	0.406	0.0517	No
14	CCR5	1422259_a_at 1422260_x_at 1424727_at	3504	0.350	0.0370	No
15	IL18R1	1421628_at	3645	0.337	0.0353	No
16	STAT4	1448713_at	3663	0.336	0.0392	No
17	JAK2	1421065_at 1421066_at	3805	0.324	0.0373	No
18	MAP2K6	1426850_a_at 1459292_at	4140	0.298	0.0261	No
19	IL12A	1425454_a_at	4279	0.290	0.0239	No
20	IL4	1449864_at	4912	0.257	-0.0015	No
21	STAT3	1424272_at 1426587_a_at 1459961_a_at 1460700_at	5150	0.246	-0.0089	No
22	CD86	1420404_at 1449858_at	5473	0.232	-0.0204	No
23	IL18RAP	1421291_at 1456545_at	6037	0.211	-0.0432	No
24	TYK2	1417306_at	6139	0.207	-0.0450	No
25	MAP2K3	1425456_a_at 1451714_a_at	7235	0.171	-0.0927	No
26	RIPK2	1421236_at 1450173_at	8147	0.145	-0.1324	No
27	IFNG	1425947_at	8785	0.130	-0.1598	No
28	IL2RA	1420691_at 1420692_at	9422	0.113	-0.1873	No
29	TNF	1419607_at	9455	0.113	-0.1872	No
30	CD3E	1422105_at 1445748_at	9934	0.101	-0.2077	No
31	IL13	1420802_at	10244	0.094	-0.2205	No
32	IRF1	1448436_a_at	10257	0.094	-0.2197	No
33	IL17A	1421672_at	10270	0.093	-0.2190	No
34	IL1B	1449399_a_at	10824	0.081	-0.2432	No
35	RAN	1443131_at 1446819_at 1447478_at 1460551_at	11162	0.073	-0.2576	No
36	CD80	1427717_at 1432826_a_at 1440592_at 1451950_a_at 1454372_at 1457952_at	12112	0.050	-0.3004	No
37	CCL4	1421578_at	12860	0.033	-0.3341	No
38	EOMES	1426001_at 1435172_at	13142	0.025	-0.3466	No
39	MAP3K14	1422999_at 1434364_at	13536	0.014	-0.3644	No
40	IL18	1417932_at	13729	0.009	-0.3731	No
41	ERC1	1421501_a_at 1424247_at 1441493_at 1444356_at 1451279_at	14036	0.001	-0.3871	No
42	NFKB2	1425902_a_at 1429128_x_at	14187	-0.004	-0.3939	No
43	REL	1420710_at	14232	-0.005	-0.3959	No
44	JUN	1417409_at 1448694_at	14497	-0.014	-0.4078	No
45	IL6	1450297_at	14615	-0.017	-0.4129	No
46	SRC	1423240_at 1450918_s_at	14992	-0.030	-0.4297	No
47	GZMB	1419060_at	15496	-0.049	-0.4520	No
48	IL1R1	1448950_at 1459777_at	15605	-0.052	-0.4563	No
49	FASLG	1418803_a_at 1449235_at	15860	-0.064	-0.4670	No
50	IKBKG	1421208_at 1421209_s_at 1435646_at 1435647_at 1450161_at 1454690_at	15968	-0.069	-0.4709	No
51	GADD45B	1420197_at 1449773_s_at 1450971_at	16031	-0.072	-0.4728	No
52	XPO1	1418442_at 1418443_at 1448070_at	16219	-0.081	-0.4802	No
53	PRKCA	1427562_a_at 1443069_at 1445028_at 1445395_at 1446598_at 1450945_at	16402	-0.092	-0.4873	No
54	SYK	1418261_at 1418262_at 1425797_a_at 1457239_at	16497	-0.099	-0.4902	No
55	NFKB1	1427705_a_at 1442949_at	16630	-0.107	-0.4947	No
56	MAPK9	1421876_at 1421877_at 1421878_at	16802	-0.119	-0.5009	No
57	CYLD	1429617_at 1429618_at 1445213_at	17002	-0.135	-0.5081	No
58	BCL10	1418970_a_at 1418971_x_at 1418972_at 1443524_x_at	17549	-0.185	-0.5306	No
59	ETV5	1420998_at 1428142_at 1450082_s_at	17851	-0.217	-0.5413	No
60	IL27RA	1449508_at	17952	-0.230	-0.5427	No
61	STAT5A	1421469_a_at 1450259_a_at	18008	-0.239	-0.5418	No
62	IL12B	1419530_at 1449497_at	18037	-0.244	-0.5397	No
63	STAT2	1421911_at 1450403_at	18138	-0.258	-0.5407	No
64	ATF2	1426582_at 1426583_at 1427559_a_at 1437777_at 1452116_s_at 1459237_at	18187	-0.264	-0.5392	No
65	EBI3	1449222_at	18256	-0.275	-0.5384	No
66	SPHK2	1417431_a_at 1426230_at	18457	-0.301	-0.5434	No
67	GADD45G	1453851_a_at	18657	-0.330	-0.5479	No
68	STAT6	1421708_a_at 1426353_at	19177	-0.434	-0.5656	No
69	RELA	1419536_a_at	19403	-0.485	-0.5691	No
70	B2M	1427511_at 1449289_a_at 1452428_a_at	19610	-0.541	-0.5710	Yes
71	PIK3R1	1425514_at 1425515_at 1438682_at 1444591_at 1451737_at	19644	-0.549	-0.5648	Yes
72	LCK	1425396_a_at 1439145_at 1439146_s_at 1457917_at	19798	-0.593	-0.5636	Yes
73	FBXW11	1425461_at 1425462_at 1437468_x_at 1438336_at 1443010_at 1447294_at 1457485_at	19839	-0.606	-0.5569	Yes
74	PIAS2	1419454_x_at 1426456_a_at 1428725_at	19878	-0.614	-0.5501	Yes
75	ARRB2	1426239_s_at 1451987_at	20060	-0.681	-0.5488	Yes
76	IL2RB	1417546_at 1448759_at 1459870_x_at	20207	-0.738	-0.5452	Yes
77	TNFRSF1A	1417291_at	20509	-0.875	-0.5468	Yes
78	PRF1	1451862_a_at	20611	-0.927	-0.5384	Yes
79	CHUK	1417091_at 1428210_s_at 1451383_a_at	20646	-0.945	-0.5268	Yes
80	FOS	1423100_at	20795	-1.059	-0.5188	Yes
81	BIRC2	1418854_at	20801	-1.062	-0.5041	Yes
82	SOCS1	1440047_at 1450446_a_at	20823	-1.082	-0.4900	Yes
83	CD8A	1440164_x_at 1440811_x_at	20843	-1.091	-0.4756	Yes
84	CD3G	1419178_at	20877	-1.120	-0.4615	Yes
85	BCL3	1418133_at	21029	-1.282	-0.4504	Yes
86	CD3D	1422828_at	21050	-1.299	-0.4332	Yes
87	CD4	1419696_at 1427779_a_at	21103	-1.360	-0.4166	Yes
88	IL6ST	1421239_at 1437303_at 1452843_at 1460295_s_at	21110	-1.370	-0.3977	Yes
89	GATA3	1448886_at	21135	-1.401	-0.3792	Yes
90	IL2RG	1416295_a_at 1416296_at	21158	-1.424	-0.3603	Yes
91	RELB	1417856_at	21176	-1.451	-0.3408	Yes
92	FRAP1	1417592_at 1436267_a_at 1446185_at 1459625_at	21257	-1.565	-0.3226	Yes
93	JAK1	1433803_at 1433804_at 1433805_at	21465	-1.953	-0.3048	Yes
94	NFKBIA	1420088_at 1420089_at 1438157_s_at 1448306_at 1449731_s_at	21592	-2.242	-0.2792	Yes
95	CD8B	1426170_a_at 1446372_at 1448569_at 1458652_at	21641	-2.425	-0.2475	Yes
96	IKBKB	1426207_at 1426333_a_at 1432275_at 1445141_at 1454184_a_at	21683	-2.583	-0.2132	Yes
97	CD28	1417597_at 1437025_at 1443703_at	21746	-2.866	-0.1760	Yes
98	CD247	1420716_at 1426079_at 1426396_at 1428059_at 1428060_at 1438392_at 1452539_a_at	21807	-3.219	-0.1338	Yes
99	TGFB1	1420653_at 1445360_at	21809	-3.227	-0.0887	Yes
100	STAT1	1420915_at 1440481_at 1450033_a_at 1450034_at	21816	-3.247	-0.0436	Yes
101	CREBBP	1434633_at 1435224_at 1436983_at 1444856_at 1457641_at 1459804_at	21856	-3.508	0.0037	Yes